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Johannes Czernin Selected Research

Pharmaceutical Preparations

10/2021Safety of PSMA-Targeted Molecular Radioligand Therapy with 177Lu-PSMA-617: Results from the Prospective Multicenter Phase 2 Trial RESIST-PC (NCT03042312).
2/2013LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin.
1/2008Technology Insight: novel imaging of molecular targets is an emerging area crucial to the development of targeted drugs.
12/2006Predicting chemotherapy response to paclitaxel with 18F-Fluoropaclitaxel and PET.
11/2005Estimation of paclitaxel biodistribution and uptake in human-derived xenografts in vivo with (18)F-fluoropaclitaxel.
1/2005Monitoring antiproliferative responses to kinase inhibitor therapy in mice with 3'-deoxy-3'-18F-fluorothymidine PET.

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Johannes Czernin Research Topics

Disease

85Neoplasms (Cancer)
11/2022 - 01/2002
44Prostatic Neoplasms (Prostate Cancer)
11/2022 - 04/2009
15Glioma (Gliomas)
03/2020 - 06/2005
12Sarcoma (Soft Tissue Sarcoma)
01/2022 - 02/2008
9Neoplasm Metastasis (Metastasis)
01/2022 - 07/2014
6Glioblastoma (Glioblastoma Multiforme)
09/2018 - 06/2008
6Lung Neoplasms (Lung Cancer)
01/2017 - 06/2002
6Brain Neoplasms (Brain Tumor)
04/2013 - 06/2005
5Adenocarcinoma
11/2022 - 01/2021
5Neuroendocrine Tumors (Neuroendocrine Tumor)
01/2022 - 01/2015
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2017 - 10/2006
5Lymphoma (Lymphomas)
09/2013 - 07/2003
5Breast Neoplasms (Breast Cancer)
12/2007 - 09/2005
4Leukemia
03/2020 - 03/2014
3Bites and Stings (Sting)
11/2022 - 01/2021
3Ataxia Telangiectasia (Louis Bar Syndrome)
11/2022 - 01/2017
3Necrosis
01/2022 - 10/2008
3Melanoma (Melanoma, Malignant)
05/2014 - 03/2002
3Non-Hodgkin Lymphoma (Lymphosarcoma)
11/2004 - 07/2003
3Hodgkin Disease (Hodgkin's Disease)
11/2004 - 08/2003
2Pancreatic Neoplasms (Pancreatic Cancer)
11/2022 - 01/2021
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2017 - 03/2014
2Hematologic Neoplasms (Hematological Malignancy)
11/2014 - 03/2014
2Hypoxia (Hypoxemia)
01/2012 - 01/2006
1Infections
06/2022
1Fibrosis (Cirrhosis)
01/2022
1Anemia
10/2021
1Gastrointestinal Hemorrhage (Hematochezia)
10/2021
1Subdural Hematoma (Subdural Hemorrhage)
10/2021
1Thyroiditis
10/2021
1Thrombocytopenia (Thrombopenia)
10/2021
1Acute Kidney Injury (Acute Renal Failure)
10/2021
1Esophageal Neoplasms (Esophageal Cancer)
02/2021
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2021

Drug/Important Bio-Agent (IBA)

28AntigensIBA
10/2022 - 06/2015
20Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
06/2022 - 04/2005
20Glucose (Dextrose)FDA LinkGeneric
01/2017 - 03/2002
17gallium 68 PSMA-11IBA
01/2022 - 06/2015
13Biomarkers (Surrogate Marker)IBA
11/2022 - 06/2005
9Prostate-Specific Antigen (Semenogelase)IBA
01/2022 - 04/2012
9fluorodopa F 18IBA
03/2020 - 06/2006
6Proteins (Proteins, Gene)FDA Link
11/2022 - 01/2008
6Phosphotransferases (Kinase)IBA
11/2022 - 01/2005
6Pharmaceutical PreparationsIBA
10/2021 - 01/2005
6Amino AcidsFDA Link
10/2014 - 06/2006
6Bevacizumab (Avastin)FDA Link
07/2014 - 10/2007
5alovudineIBA
01/2022 - 06/2005
5LigandsIBA
01/2022 - 11/2016
5FAPI-46IBA
01/2022 - 01/2020
5GemcitabineFDA Link
07/2013 - 02/2009
4NucleotidesIBA
11/2022 - 03/2014
4AndrogensIBA
10/2021 - 04/2012
4ThymidineIBA
01/2021 - 01/2006
4ErbB Receptors (EGF Receptor)IBA
01/2017 - 10/2006
4ProdrugsIBA
01/2017 - 02/2009
4NucleosidesIBA
02/2012 - 02/2009
3InterferonsIBA
11/2022 - 01/2021
3Somatostatin Receptors (Somatostatin Receptor)IBA
01/2022 - 01/2015
3177Lu-PSMA-617IBA
10/2021 - 11/2017
3Radioisotopes (Radionuclides)IBA
01/2021 - 10/2016
3gallium Ga 68 dotatateIBA
11/2017 - 01/2015
3EnzymesIBA
01/2017 - 08/2009
3Deoxycytidine KinaseIBA
01/2017 - 09/2013
3Peptides (Polypeptides)IBA
11/2016 - 04/2011
3Irinotecan (Camptosar)FDA LinkGeneric
10/2011 - 10/2007
3MTOR InhibitorsIBA
08/2009 - 01/2006
2Interferon Type IIBA
11/2022 - 01/2021
2DNA (Deoxyribonucleic Acid)IBA
06/2022 - 03/2014
2thymidine kinase 1IBA
01/2022 - 06/2012
2Immune Checkpoint InhibitorsIBA
10/2021 - 01/2021
2thiamine triphosphorate (TTP)IBA
01/2021 - 10/2020
2Protein Kinases (Protein Kinase)IBA
03/2020 - 06/2008
2Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2017 - 11/2011
2Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
01/2017 - 09/2013
2Acetates (Acetic Acid Esters)FDA Link
10/2016 - 04/2009
2Cytidine DeaminaseIBA
04/2016 - 02/2012
22'-deoxycytidine 5'-triphosphate (dCTP)IBA
03/2014 - 09/2013
2Clofarabine (Clolar)FDA Link
02/2012 - 04/2011
2Biological ProductsIBA
01/2012 - 03/2010
2Cytarabine (Cytosar-U)FDA LinkGeneric
04/2011 - 02/2009
2Sirolimus (Rapamycin)FDA Link
08/2009 - 06/2008
2Deoxyglucose (2 Deoxy D glucose)IBA
08/2009 - 01/2002
2TOR Serine-Threonine KinasesIBA
06/2008 - 01/2006
2Paclitaxel (Taxol)FDA LinkGeneric
12/2006 - 11/2005
2Fluorine-18IBA
06/2003 - 09/2002
1RNA (Ribonucleic Acid)IBA
06/2022
1N-acetyltalosaminuronic acid (NAT)IBA
01/2022
1Lutetium-177IBA
01/2021
1Thymidine PhosphorylaseIBA
01/2021

Therapy/Procedure

45Therapeutics
11/2022 - 06/2002
13Drug Therapy (Chemotherapy)
02/2022 - 08/2003
13Radiotherapy
01/2022 - 01/2012
10Castration
11/2022 - 07/2014
8Prostatectomy (Retropubic Prostatectomy)
01/2022 - 01/2018
8Neoadjuvant Therapy
01/2022 - 02/2008
4Immunotherapy
01/2021 - 01/2017
4Aftercare (After-Treatment)
06/2008 - 07/2003
3Precision Medicine
01/2022 - 01/2018
3Lymph Node Excision (Lymph Node Dissection)
11/2021 - 10/2005
2Intravenous Injections
06/2006 - 04/2005